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Purpose
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A serine protease inhibitor
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Characteristics
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An irreversible inhibitor of serine proteases (such as thrombin, trypsin and chymotrypsin) and mammalian acetylcholinesterase. It causes sulfonylation of the active-site serine residues. Inhibits cysteine proteases like papain (reversible by DTT treatment). Also inhibits internucleosomal DNA fragmentation in immature thymocytes.
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Purity
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≥ 99?%
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Chemical Name
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α-Toluenesulfonyl fluoride, Benzylsulfonyl fluoride, Phenylmethylsulfonyl fluoride
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Formula
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C?H?FO?S
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Permeability
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Not-permeable
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Solubility
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EtOH (10%)
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