產(chǎn)品詳情
簡(jiǎn)單介紹:
SIRT2Inhibitor,B2
詳情介紹:
Purpose | A potent SIRT2 inhibitor |
Characteristics |
Cell-permeable. A Sirtuin 2 (SIRT2) inhibitor (IC50 = 35 μM). Promotes inclusion formation in cellular models of both Huntington,'s disease and Parkinson,'s disease. Prevents huntingtin-mediated proteasome dysfunction and reduces alpha-synuclein-mediated toxicity. Synonyms: 5-[4-(4-Chlorobenzoyl)-1-piperazinyl]-8-nitroquinoline, CPNQ |
Purity | ≥ 95?% |
Chemical Name | 5-[4-(4-Chlorobenzoyl)-1-piperazinyl]-8-nitroquinoline, CPNQ |
Formula | C??H??ClN?O? |
Permeability | Cell-permeable |
Solubility | DMSO (>5 mg/mL) |
Molecular Weight | 396.83 g/mol |
CAS-No | 115687-05-3 |
Restrictions | For Research Use only |
Format | Solid |
Handling Advice | Protect from air and light |
Storage | -20 °C |
Expiry Date | 24 months |
Supplier Images |
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