產(chǎn)品詳情
簡單介紹:
ENMD-2076
詳情介紹:
Purpose | ENMD-2076 has selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1.86 nM, 25-fold selective for Aurora A than over Aurora B and less potent to VEGFR2/KDR and VEGFR3, FGFR1 and FGFR2 and PDGFRα. Phase 2. |
Characteristics |
Target: Aurora Kinase inhibitor Receptor: Aurora A,FLT3/RET/VEGFR3 |
Purification | All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality. |
Purity | 97?% + |
Formula | C25H31N7O6 |
Solubility | 100 mM in DMSO |
Molecular Weight | 525.56 g/mol |
CAS-No | 934353-76-1 |
Application Notes | Optimal working dilution should be determined by the investigator. |
Restrictions | For Research Use only |
Format | Solid |
Storage | -20 °C |
Storage Comment |
For the majority of compounds, they could be dissolved in DMSO or other organic solvent. Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience. Several freeze/thaw cycles should not damage the activity of our small molecule products. However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours. |
Expiry Date | 24 months |