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  • 產(chǎn)品名稱：BIX02189

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  • 產(chǎn)品廠商：TargetMol
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簡單介紹：
BIX02189
詳情介紹：
Purpose BIX02189 is a selective inhibitor of MEK5 with IC50 of 1.5 nM, also inhibits ERK5 catalytic activity with IC50 of 59 nM in cell-free assays, and does not inhibit closely related kinases MEK1, MEK2, ERK2, and JNK2.
Characteristics Target: MEK inhibitor
Receptor: MEK5/ERK5/TGFβ/MEK1/ERK1/JNK1/EGFR/STK16
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 97?% +
Formula C27H28N4O2
Solubility 100 mM in DMSO
Molecular Weight 440.54 g/mol
CAS-No 1094614-85-3
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months
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