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  • 產(chǎn)品名稱：LY-2874455

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  • 產(chǎn)品廠商：TargetMol
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簡(jiǎn)單介紹：
LY-2874455
詳情介紹：
Purpose LY2874455 is a pan-FGFR inhibitor with IC50 of 2.8 nM, 2.6 nM, 6.4 nM, and 6 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively, and also inhibits VEGFR2 activity with IC50 of 7 nM. Phase 1.
Characteristics Target: FGFR inhibitor, VEGFR inhibitor
Receptor: FGFR2/FGFR1/FGFR3/FGFR4,VEGFR2
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 97?% +
Formula C21H19Cl2N5O2
Solubility 100 mM in DMSO and ethanol
Molecular Weight 444.31 g/mol
CAS-No 1254473-64-7
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months
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