久热精品人妻视频,人人妻人人妻人人av,亚洲无码天堂在线观看,澳门成AV人片在线观看无码,久久国产精品二区,亚洲无码免费观看视频

產(chǎn)品詳情

  • 產(chǎn)品名稱：ADWX-1

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：BioLeaf
  • 產(chǎn)品文檔：
你添加了1件商品 查看購(gòu)物車
簡(jiǎn)單介紹：
ADWX-1
詳情介紹：
Sequence VGINVKCKHS RQCLKPCKDA GMRFGKCTNG KCHCTPK.
Specificity Voltage-gated channel (Kv1.3 and Kv1.1) blocker. ADWX-1 blocks Kv1.3 channels with IC50 of 019 nM, and inhibits Kv1.1 channels with IC50 of 0.65nM.
Characteristics Source: Mesobuthus Martensii (Buthus martensii).
Molecular formula: C169H281N57O46S7.
Disulfide bonds between Cys7-Cys27, Cys13-Cys32, and Cys17-Cys34.
Purity > 98 %
Background ADWX-1 inhibits Kv1.3 channels heterologously expressed in HEK-293 cells. Kv1.3 channel currentsbefore and after application of 10pM ADWX-1. Kv1.3 channel currents were elicited by depolarizing the voltage steps of 200 ms from the holding potential -80 mV to +50 mV.
Molecular Weight 4072
Application Notes 019-0.65nM
Restrictions For Research Use only
Format Lyophilized
Reconstitution Any aqueous buffer. Centrifuge all product preparations before use (10000 x g 5 min).
Concentration after reconstitution: Dissolving 50g in 1.228ml will provide a stock solution of 10M.
Handling Advice Soluble in Water.
Supplier Images
image for ADWX-1 (ABIN1001633) Kv1.3 channel currents, before and after application of 10pM ADWX-1. Kv1.3 channel cu...
Product cited in: Yin, Jiang, Yi, Han, Yang, Liu, Liu, Cao, Wu, Li: "Different residues in channel turret determining the selectivity of ADWX-1 inhibitor peptide between Kv1.1 and Kv1.3 channels." in: Journal of proteome research, Vol. 7, Issue 11, pp. 4890-7, 2008 (PubMed).

Han, Yi, Yin, Chen, Liu, Cao, Wu, Li: "Structural basis of a potent peptide inhibitor designed for Kv1.3 channel, a therapeutic target of autoimmune disease." in: The Journal of biological chemistry, Vol. 283, Issue 27, pp. 19058-65, 2008 (PubMed).

阿拉善盟| 山东省| 巢湖市| 公主岭市| 株洲市| 保山市| 大方县| 胶南市| 馆陶县| 土默特右旗| 永靖县| 青川县| 封开县| 太仓市| 乐陵市| 广安市| 泾源县| 小金县| 北海市| 南康市| 奈曼旗| 抚顺市| 汉源县| 福鼎市| 安吉县| 时尚| 奉新县| 阿城市| 三门县| 昌江| 平阴县| 崇州市| 皋兰县| 白城市| 建湖县| 永嘉县| 滦平县| 临城县| 阿拉善盟| 焦作市| 弋阳县|