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產(chǎn)品詳情

  • 產(chǎn)品名稱：FolliculogenesisSpecificBasicHelix-Loop-Helix(FIGLA)(C-Term)Peptide

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簡單介紹：
FolliculogenesisSpecificBasicHelix-Loop-Helix(FIGLA)(C-Term)Peptide
詳情介紹：
Blocked Antibody anti-FIGLA antibody (Folliculogenesis Specific Basic Helix-Loop-Helix) (C-Term) (ABIN2779982)
Sequence SSTRELLGNA TQPTSCASGL KKEEEGPWAY AGHSEPLYSY HQSTVPETRS
Characteristics This is a synthetic peptide designed for use in combination with anti-Figla Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background Figla is a germ-line specific transcription factor implicated in postnatal oocyte-specific gene expression. It plays a key regulatory role in the expression of multiple oocyte-specific genes, including those that initiate folliculogenesis and those that encode the zona pellucida (ZP1, ZP2 and ZP3) required for fertilization and early embryonic survival. It is essential for oocytes to survive and form primordial follicles. The persistence of FIGLA in ***** females suggests that it may regulate additional pathways that are essential for normal ovarian development. Figla binds to the E-box (5'-CANNTG-3') of the ZPs (ZP1, ZP2, ZP3) promoters.

Alias Symbols: bHLHc8

Protein Size: 194
Molecular Weight 21 kDa
Gene ID 26910
NCBI Accession NM_012013, NP_036143
UniProt O55208
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100?μL of sterile PBS. Final peptide concentration is 1?mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeat freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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