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Background
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Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1).
Alias Symbols: NMT
Protein Interaction Partner: MARCKS,MoV3sM2gp1,PRKACA,ANXA13,ARL5A,CABP2,CAPN2,FYN,GNAZ,HPCA,LYN,MARCKS,NOS3,SRC,TP53,CABP1,CABP2,FYN,LYN
Protein Size: 496
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