久热精品人妻视频,人人妻人人妻人人av,亚洲无码天堂在线观看,澳门成AV人片在线观看无码,久久国产精品二区,亚洲无码免费观看视频

產(chǎn)品詳情
所在位置: 首頁> 產(chǎn)品目錄> 試劑>
  • 產(chǎn)品名稱:Boc-D-FMK

  • 產(chǎn)品型號:
  • 產(chǎn)品廠商:Biovision
  • 產(chǎn)品文檔:
你添加了1件商品 查看購物車
簡單介紹:
Boc-D-FMK
詳情介紹:
Purpose A caspase family inhibitor
Sequence Boc-Asp(OMe)-FMK
Characteristics A synthetic peptide that irreversibly inhibits activity of caspase family proteases and blocks apoptosis. The inhibitor is designed as a methyl ester to facilitate cell permeability. The product can be used for both in vitro and in vivo studies. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).
Purity > 95?% by HPLC
Chemical Name Boc-D-FMK, Boc-D-fluoromethylketone, Caspase Inhibitor (fluoromethylketone)
Formula C??H??FNO?
Permeability Cell-permeable
Solubility DMSO (20 mM)
Molecular Weight 263.26 g/mol
Application Notes We recommend using 2-10 μM for inhibiting caspase activity in cell culture.
The optimal doses may vary for different cells and culture conditions.
Restrictions For Research Use only
Format Solid, Lyophilized
Handling Advice Protect from light and moisture
Storage -20 °C
Expiry Date 12 months
Product cited in: Natoni, Murillo, Kliszczak, Catherwood, Montagnoli, Samali, ODwyer, Santocanale: "Mechanisms of action of a dual Cdc7/Cdk9 kinase inhibitor against quiescent and proliferating CLL cells." in: Molecular cancer therapeutics, Vol. 10, Issue 9, pp. 1624-34, 2011 (PubMed).

Oshikawa, Nagao, Wu, Kurosu, Miura: "c-Cbl and Cbl-b ligases mediate 17-allylaminodemethoxygeldanamycin-induced degradation of autophosphorylated Flt3 kinase with internal tandem duplication through the ubiquitin proteasome pathway." in: The Journal of biological chemistry, Vol. 286, Issue 35, pp. 30263-73, 2011 (PubMed).

Kurosu, Ohki, Wu, Kagechika, Miura: "Sorafenib induces apoptosis specifically in cells expressing BCR/ABL by inhibiting its kinase activity to activate the intrinsic mitochondrial pathway." in: Cancer research, Vol. 69, Issue 9, pp. 3927-36, 2009 (PubMed).

平阳县| 二连浩特市| 新巴尔虎左旗| 交口县| 余庆县| 文水县| 蓝山县| 简阳市| 广河县| 六枝特区| 南溪县| 南阳市| 凤凰县| 荣成市| 永靖县| 马鞍山市| 息烽县| 嘉义市| 无棣县| 黎城县| 平罗县| 邵阳市| 娄烦县| 六盘水市| 洪洞县| 漳浦县| 中阳县| 城固县| 新津县| 静海县| 镇原县| 淳化县| 扬中市| 乌兰县| 新蔡县| 桦甸市| 道真| 竹溪县| 蒙城县| 宿迁市| 苍梧县|