產(chǎn)品詳情
簡(jiǎn)單介紹:
CaspaseFamilyInhibitorSetIV
詳情介紹:
Purpose | Caspase family inhibitors |
Characteristics | A convenient set containing twelve ready-to-use capase family inhibitors. The set contains 25 μl (2 mM in DMSO) each of the following five inhibitors: Caspase-1 Inhibitor, Z-YVAD(OMe)-FMK, Caspase-2 Inhibitor, Z-VD(OMe)-VAD(OMe)-FMK, Caspase-3 Inhibitor, Z-D(OMe)-E(OMe)-VD(OMe)-FMK, ?Caspase-4 Inhibitor, Z-LE(OMe)VD(OMe)-FMK, Caspase-5 Inhibitor, Z-WE(OMe)HD(OMe)-FMK, Caspase-6 Inhibitor, Z-VE(OMe)ID(OMe)-FMK, Caspase-8 Inhibitor, Z-IE(OMe)TD(OMe)-FMK , Caspase-9 Inhibitor, Z-LE(OMe)HD(OMe)-FMK, Caspase-10 Inhibitor, Z-AE(OMe)VD(OMe)-FMK, Caspase-13 Inhibitor, Z-LE(OMe)E(OMe)D(OMe)-FMK, pan Caspase Inhibitor, Z-VAD(OMe)-FMK and the negatuve control, Z-FA-FMK. |
Formula | See under the individual product |
Permeability | Cell-permeable |
Solubility | DMSO (2 mM) |
Application Notes |
We recommend using 1000X dilutions for inhibiting caspase activity in Jurkat cell culture (e.g., Add 1 μL to 1 mL of culture medium). However the optimal doses may vary for different cells and culture conditions. Note: All inhibitors were formulated in 100 % pure DMSO. |
Restrictions | For Research Use only |
Format | Liquid |
Handling Advice | Protect from air, light and moisture |
Storage | -20 °C |
Expiry Date | 12 months |
Product cited in: |
Wang, Van Antwerp, Kuick, Gauger, Doherty, Fan, Baker: "Microarray analysis of cytokine activation of apoptosis pathways in the thyroid." in: Endocrinology, Vol. 148, Issue 10, pp. 4844-52, 2007 (PubMed).
Aleman, DeYoung, Tress, Keating, Perry, Narayanan: "Inhibition of Single Minded 2 gene expression mediates tumor-selective apoptosis and differentiation in human colon cancer cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 36, pp. 12765-70, 2005 (PubMed). |