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  • 產(chǎn)品名稱：TG101209

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  • 產(chǎn)品廠商：TargetMol
  • 產(chǎn)品文檔：
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簡單介紹：
TG101209
詳情介紹：
Purpose TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM, less potent to Flt3 and RET with IC50 of 25 nM and 17 nM in cell-free assays, ~30-fold selective for JAK2 than JAK3, sensitive to JAK2V617F and MPLW515L/K mutations.
Characteristics Target: JAK inhibitor, FLT3 inhibitor, RET inhibitor
Receptor: JAK2,RET,FLT3,JAK3
Status: Undetermined activity
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 100?%
Formula C26H35N7O2S
Solubility DMSO 102 mg/mL,Water <1 mg="" ml="" <="" td="">
Molecular Weight 509.67 g/mol
CAS-No 936091-14-4
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months
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