Purpose
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D 4476 is a potent, selective, and cell-permeant CK1 (casein kinase 1) inhibitor with IC50 of 200 nM and 300 nM in a cell-free assay for CK1 from Schizosaccharomyces pombe and CK1δ, respectively. Also acts as an ALK5 inhibitor with IC50 of 500 nM.
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Characteristics
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Target: Casein Kinase inhibitor Receptor: CK1from Schizosaccharomyces pombe,CK1δ,ALK5
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Purification
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All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
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Purity
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100?%
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Formula
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C23H18N4O3
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Permeability
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Cell-permeable
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Solubility
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200 mM in DMSO
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