Purpose
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SGI-1776 free base is a novel ATP competitive inhibitor of Pim1 with IC50 of 7 nM in a cell-free assay, 50- and 10-fold selective versus Pim2 and Pim3, also potent to Flt3 and haspin. Phase 1.
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Characteristics
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Target: Pim inhibitor, FLT3 inhibitor Receptor: Pim1, FLT3, Pim3,Pim2 Status: Experimental
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Purification
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All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
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Purity
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100?%
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Formula
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C20H22F3N5O
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Solubility
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DMSO 81 mg/mL,Ethanol 81 mg/mL,Water <1 mg="" ml="" <="" td="">
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