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產(chǎn)品名稱:AT9283
產(chǎn)品型號(hào):
產(chǎn)品廠商:TargetMol
產(chǎn)品文檔:
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簡單介紹:
AT9283
詳情介紹:
Product details
Product details
Purpose
AT9283 is a potent JAK2/3 inhibitor with IC50 of 1.2 nM/1.1 nM in cell-free assays, also potent to Aurora A/B, Abl(T315I). Phase 2.
Characteristics
Target: JAK inhibitor, Aurora Kinase inhibitor, Bcr-Abl inhibitor, GSK-3 inhibitor, FGFR inhibitor
Receptor: JAK3,JAK2,Aurora A,Aurora B,Abl1,GSK-3β, FGFR2,VEGFR3/FLT4
Status: Experimental
Purification
All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity
98.45?%
Formula
C19H23N7O2
Solubility
DMSO 76 mg/mL,Ethanol 38 mg/mL,Water <1 mg="" ml="" <="" td=""> 1>
Target details
Target details
Molecular Weight
381.43 g/mol
CAS-No
896466-04-9
Application Details
Application Details
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
Handling
Format
Solid
Storage
-20 °C
Storage Comment
For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date
24 months
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