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產(chǎn)品詳情

  • 產(chǎn)品名稱：BMS-754807

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：TargetMol
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
BMS-754807
詳情介紹：
Purpose BMS-754807 is a potent and reversible inhibitor of IGF-1R/InsR with IC50 of 1.8 nM/1.7 nM in cell-free assays, less potent to Met, Aurora A/B, TrkA/B and Ron, and shows little activity to Flt3, Lck, MK2, PKA, PKC etc. Phase 2.
Characteristics Target: IGF-1R inhibitor, c-MET inhibitor, Aurora Kinase inhibitor, FLT3 inhibitor, JAK inhibitor
Receptor: IGF-1R, Insulin Receptor,TrkB,Met,TrkA,Aurora A,Aurora B,RON,FLT3,JAK2
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 97?% +
Formula C23H24FN9O
Solubility 200 mM in DMSO and ethanol
Molecular Weight 461.49 g/mol
CAS-No 1001350-96-4
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months
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