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Purpose
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JNK-IN-8 is the first irreversible JNK inhibitor for JNK1, JNK2 and JNK4 with IC50 of 4.7 nM, 18.7 nM and 1 nM, >10-fold selectivity against MNK2, Fms and no inhibition to c-Kit, Met, PDGFRβin A375 cell line.
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Characteristics
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Target: JNK inhibitor
Receptor: JNK3,JNK1,JNK2,Kit,MNK2
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Purification
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All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
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Purity
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100?%
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Formula
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C29H29N7O2
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Solubility
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200 mM in DMSO
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