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  • 產(chǎn)品名稱:MLN2238(Ixazomib)

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  • 產(chǎn)品廠商:TargetMol
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簡單介紹:
MLN2238(Ixazomib)
詳情介紹:
Purpose MLN2238 inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50 and Ki of 3.4 nM and 0.93 nM in cell-free assays, respectively, also inhibits the caspase-like (β1) and trypsin-like (β2) proteolytic sites, with IC50 of 31 and 3500 nM. Phase 3.
Characteristics Tradename: Ixazomib
Target: Proteasome inhibitor
Receptor: 20S proteasome
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 98?%
Formula C14H19BCl2N2O4
Solubility Soluble in DMSO
Molecular Weight 361.03 g/mol
CAS-No 1072833-77-2
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months
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