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  • 產(chǎn)品名稱：Pyridone6

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  • 產(chǎn)品廠商：TargetMol
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Pyridone6
詳情介紹：
Purpose Pyridone 6(CMP 6) is a potent and selective inhibitor of JAK1 (IC50=15 nM, murine JAK1), JAK2 (IC50=1 nM), JAK3 (Ki=5 nM), and Tyk2 (IC50=1 nM), displaying significantly weaker affinities (130 nM to 10 mM) for other protein tyrosine kinases.
Characteristics Tradename: Merck-5
Target: JAK inhibitor
Receptor: JAK1/JAK2/JAK3/Try2
Status: Undetermined activity
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 98.74?%
Formula C18H16FN3O
Solubility DMSO 5mg
Molecular Weight 309.34 g/mol
CAS-No 457081-03-7
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months
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