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  • 產(chǎn)品名稱：AEE788

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  • 產(chǎn)品廠商：TargetMol
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AEE788
詳情介紹：
Purpose AEE788 (NVP-AEE788) is a potent inhibitor of EGFR and HER2/ErbB2 with IC50 of 2 nM and 6 nM, less potent to VEGFR2/KDR, c-Abl, c-Src, and Flt-1, does not inhibit Ins-R, IGF-1R, PKCα and CDK1. Phase 1/2.
Characteristics Target: EGFR inhibitor, Bcr-Abl inhibitor, Src inhibitor, HER2 inhibitor
Receptor: EGFR/c-Abl/FLT1/c-Src, HER2/ErbB2, HER4/ErbB4
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 98?%
Formula C27H32N6
Solubility 100 mM in DMSO
Molecular Weight 440.58 g/mol
CAS-No 497839-62-0
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months
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