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Background
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Synthetic Elcatonin is a single, non-glycosylated polypeptide chain containing 31 amino acids, and a molecular formula of C148H244N42O47. Elcatonin is a calcitonin derivative, which is transformed from eel?s calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. In addition, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits the renal tubules from reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by osteoporosis.
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