久热精品人妻视频,人人妻人人妻人人av,亚洲无码天堂在线观看,澳门成AV人片在线观看无码,久久国产精品二区,亚洲无码免费观看视频

產(chǎn)品詳情
  • 產(chǎn)品名稱:rCharybdotoxin

  • 產(chǎn)品型號:
  • 產(chǎn)品廠商:BioLeaf
  • 產(chǎn)品文檔:
你添加了1件商品 查看購物車
簡單介紹:
rCharybdotoxin
詳情介紹:
Sequence QFTNVSCTTS KECWSVCQRL HNTSRGKCMN KKCRCYS.
Specificity Charybdotoxin is a potent selective inhibitor of high conductance (maxi-K), different medium and small conductance Ca2+-activated K+ channels, as well as a voltage-dependent K+ channel (Kv1.3).
Characteristics Source: Leiurus quinquestriatus hebraeus (Yellow scorpion).
Molecular formula: C176H280N58O55S7.
Disulfide bonds between Cys7-Cys28, Cys13-Cys33, and Cys17-Cys35.
Purity > 98 %
Background Inhibition of mSlo channels heterologously expressed in HEK293 cells by Charybdotoxin. mSlo channel currents, before and during application of 100nM rCharybdotoxin. The currents were activated by a 50 ms voltage step to +100 mV from a prepulse of -180 mV with intracellular 10M Ca2+.
Molecular Weight 4313
Application Notes 10-100 nM
Comment

K+ channel toxin -KTx 1.1, ChTX, ChTX-Lq1, ChTx-a.

Restrictions For Research Use only
Format Lyophilized
Reconstitution Any aqueous buffer. Centrifuge all product preparations before use (10000 x g 5 min).
Concentration after reconstitution: Dissolving 50g in 1.160ml will provide a stock solution of 10 M.
Handling Advice Soluble in Water.
Supplier Images
 image for rCharybdotoxin (ABIN1001696) mSlo channel currents, before and during application of 100nM rCharybdotoxin. The cur...
Background publications Meera, Wallner, Toro: "A neuronal beta subunit (KCNMB4) makes the large conductance, voltage- and Ca2+-activated K+ channel resistant to charybdotoxin and iberiotoxin." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 10, pp. 5562-7, 2000 (PubMed).

Product cited in: Vita, Bontems, Bouet, Tauc, Poujeol, Vatanpour, Harvey, Menez, Toma: "Synthesis of charybdotoxin and of two N-terminal truncated analogues. Structural and functional characterisation." in: European journal of biochemistry / FEBS, Vol. 217, Issue 1, pp. 157-69, 1993 (PubMed).

Gimenez-Gallego, Navia, Reuben, Katz, Kaczorowski, Garcia: "Purification, sequence, and model structure of charybdotoxin, a potent selective inhibitor of calcium-activated potassium channels." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 85, Issue 10, pp. 3329-33, 1988 (PubMed).

Smith, Phillips, Miller: "Purification of charybdotoxin, a specific inhibitor of the high-conductance Ca2+-activated K+ channel." in: The Journal of biological chemistry, Vol. 261, Issue 31, pp. 14607-13, 1986 (PubMed).

Miller, Moczydlowski, Latorre, Phillips: "Charybdotoxin, a protein inhibitor of single Ca2+-activated K+ channels from mammalian skeletal muscle." in: Nature, Vol. 313, Issue 6000, pp. 316-8, 1985 (PubMed).

高邑县| 克拉玛依市| 西畴县| 健康| 宽城| 合川市| 翼城县| 赣榆县| 界首市| 二手房| 马关县| 敦煌市| 乐安县| 乌恰县| 巢湖市| 安顺市| 康乐县| 鹿泉市| 大方县| 洪泽县| 柏乡县| 阳原县| 托里县| 咸丰县| 威宁| 紫阳县| 陵水| 花莲市| 花莲县| 邵武市| 扎赉特旗| 金寨县| 恩施市| 车险| 兴和县| 壤塘县| 开鲁县| 二手房| 定襄县| 秦安县| 永顺县|